منابع مشابه
Oxidative Stress and Human Disease: a Review
Background: The human body needs both types of oxidants (free radicals) and antioxidants for normal metabolism, signal transduction mechanism, and the order of cellular activity. Free radicals can be either harmful or helpful to the body, in fact, they play a dual role as both toxic and beneficial compounds. The human body has the natural antioxidant defense mechanism to counteract the free rad...
متن کاملOxidative stress and acute lung injury.
Acute lung injury (ALI) and its most severe form, the acute respiratory distress syndrome (ARDS) are frequent complications in critically ill patients and are responsible for significant morbidity and mortality (1, 2). Treatment of the underlying disease and excellent supportive care using “lung-protective” strategies of mechanical ventilation (3) contribute to successful clinical outcomes. How...
متن کاملOxidative stress: acute and progressive lung injury.
Oxidative stress in lung often occurs in humans during acute lung injury (ALI) and in the acute respiratory distress syndrome. The lung inflammatory response may proceed to the development of pulmonary fibrosis, a devastating complication that occurs in premature infants after prolonged exposure to high oxygen concentrations. Oxidant-related ALI can be induced by airway deposition of lipopolysa...
متن کاملOxidative Stress and Lung Ischemia-Reperfusion Injury
Ischemia-reperfusion (IR) injury is directly related to the formation of reactive oxygen species (ROS), endothelial cell injury, increased vascular permeability, and the activation of neutrophils and platelets, cytokines, and the complement system. Several studies have confirmed the destructiveness of the toxic oxygen metabolites produced and their role in the pathophysiology of different proce...
متن کامل[Oxidative stress and Alzheimer's disease].
INTRODUCTION According to the oxidative stress hypothesis, the pathogenesis of several diseases should be related with an excessive production of prooxidant substances (free radicals, transition metals), the deficiency of antioxidant defensive mechanisms, or both. Oxidative stress has been implicated in the pathogenesis of aging of the brain and several neurological diseases, including Alzheime...
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ژورنال
عنوان ژورنال: Indian Journal of Clinical Biochemistry
سال: 2014
ISSN: 0970-1915,0974-0422
DOI: 10.1007/s12291-014-0441-5